DEM also affected the relative gene expression of nd-1 (gene of the mitochondrial DNA), as short-term treatment showed a slight trend toward lower levels, whereas long-term treatment increased the expression ( Fig. 6 C, F).
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Consequences of iron exposure and glutathione depletion on redox balance, lipidome, and neurotransmission in C. elegans.
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This class is exclusively located in the mitochondrial membrane and showed a trend toward reduced levels after 24 h DEM treatment, both alone and combined with Fe treatment ( Fig. 6 G).