BASCULE: bayesian inference and clustering of mutational signatures leveraging biological priors.

Genome Biol · 2025 · PMC12857155 · PMID 41456010

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

showed a trendp = 0.059so close (0.05 < p ≤ 0.1)

6 C), with G1 as reference due to its lowest survival outcomes, cluster G11 showed a trend toward a protective effect ( n = 190, hazard ratio = 0.63, 95% CI : 0.39–1.02, p = 0.059).

also in 53,322 other papers

borderline significantno p-value reported

This finding however was borderline significant, possibly because of the effect of age which significantly influenced the hazard: younger patients experienced a 44% reduction in risk relative to older individuals ( n = 114, hazard ratio = 0.56, 95% CI : 0.40–0.80, p = 0.001), whereas gender did not significantly affect the outcome.

also in 11,409 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.