Multifunctional bilayer scaffolds integrating melt electrowriting fibers and drug-loaded microspheres promote posteochondral regeneration through PI3K-AKT-mediated chondro-osteogenic signaling.

Mater Today Bio · 2026 · PMC12857294 · PMID 41624540

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did not reach statistical significanceno p-value reported

Notably, although HM@BlankP showed improved outcomes compared with Blank across all readouts, these changes did not reach statistical significance.

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