Barely Significant
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Comparison between traditional and digital anterior repositioning splints on the upper airway in skeletal class II malocclusion with TMJ degenerative disease.

Sci Rep · 2026 · PMC12858999 · PMID 41486329

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marginal significanceno p-value reported
On the one hand, the sample size of this study (55 cases per group) was determined based on preliminary feasibility data rather than formal power analysis, and insufficient statistical power may lead to marginal significance of the results.

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a suggestive trendno p-value reported
Therefor, in the intergroup comparisons of changes in upper airway indicators, the digital device is superior to traditional treatment in improving the minimum cross-sectional area of the upper airway, with a suggestive trend toward better outcomes in total airway volume and oropharyngeal volume.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.