Under the induction of LM@pBLP, macrophages showed an increase in the expression of HDAC7 ( P > 0.05), mTORC2 ( P < 0.01), and HIF1-α ( P < 0.01), although the increase in HDAC7 expression did not reach statistical significance ( Fig. 6 D).
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A pathogen peptidoglycan scaffold coated with artificial biomembrane promotes broad resistance to bacterial infections by dynamically reprogramming macrophage metabolism.
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