Aging-associated immune signature as a predictor of mortality in end-stage renal disease: results from the longitudinal iESRD study.

Consistently, a higher PC1 score showed a trend toward protection against infection-related mortality (Table 4 ), likely reflecting the role of lymphocytes to combat infection, whereas PC2 was associated with total leukocyte, neutrophil and monocyte counts, likely reflecting innate immune status.

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In contrast, PC3 consistently predicted cardiovascular death in univariable, Model 1, and Model 3 (with marginal significance in Model 2).

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