Our data revealed that thiamine markedly elevated the labyrinth/total placenta area ratio and showed a trend toward expansion of the placental blood sinus area, suggesting that thiamine enhances maternal–fetal nutrient exchange to meet the fetus's escalating nutritional demands.
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From maternal microbes to offspring development: gut microbiota-derived thiamine regulates the gut microbiota and drives the placental Notch pathway to coordinate angiogenesis and nutrient transport.
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