High burden of geriatric assessment impairments across the adult age spectrum in patients with cancer.

Although the association did not reach statistical significance in the youngest (20-39 years) and oldest (≥80 years) cohorts, potentially because of limited sample sizes or competing mortality risks, the overall trend was clear; higher degrees of frailty at baseline conferred a progressively increased risk of mortality.

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The distribution of cancer types was highly significant, with head and neck cancers being markedly more prevalent in younger groups (44.0% in 20-39, 48.8% in 40-49), while stomach/small bowel, liver, and colorectal cancers prevalence varied significantly by age group, with higher proportions in older age bands (eg, colorectal: 2.0% in 20-39 vs 25.6% in ≥80).

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