TSG-6 Activated MSC-derived Extracellular Vesicles Present Altered micro-RNA Contents and Ameliorate the Inflammatory Phenotype of Macrophages in Vitro.

Higher dosages tended to cause larger downregulation for CCL2 and TNF-α, albeit this effect did not reach statistical significance.

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Highly significant terms included response to hypoxia and viral reproductive process (both FDR = 5.02 × 10−6), consistent with macrophage roles in infection and tumor microenvironments.

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