Kisspeptin improves local ovarian insulin resistance in PCOS by modulating the PI3K/AKT/GLUT4 signaling pathway.

PLoS One · 2026 · PMC12863573 · PMID 41628190

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quite significantno p-value reported

In the Discussion, please comment on the observation that the rise in testosterone in the model group compared to controls is relatively modest, yet the difference in glucose tolerance test (GTT) results and HOMA-IR is quite significant.

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