ISM-1 expression in cutaneous mastocytosis: Diagnostic potential and comparison with CD117.

Medicine (Baltimore) · 2026 · PMC12863809 · PMID 41630249

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did not reach statistical significanceno p-value reported

Cases with high ISM-1 expression showed increased eosinophil counts; however, this trend did not reach statistical significance. These findings suggest that ISM-1 may serve as a complementary immunohistochemical marker for mast cell detection, particularly in diagnostically challenging cases.

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