Regarding ISG15+ TAMs, TCGA pan-cancer analysis showed a trend toward worse OS and DSS, although the association was not as strong as that of THBS1+ MDSCs–SPP1+ TAMs or C1QC+ TAMs (Supplementary Fig.
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Pan-Cancer Single-Cell RNA Sequencing Analysis Refines Multi-Origin Monocyte and Macrophage Lineages.
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