CSF metabolomic signature during therapy for childhood acute lymphoblastic leukemia predicts subsequent working memory impairment.

Mol Med · 2025 · PMC12865937 · PMID 41469545

Europe PMC DOI

hedged sentence

0.0740

closest p · 1.5× alpha

0.0740

boldest claim

The sentences

did not reach statistical significancep = 0.074so close (0.05 < p ≤ 0.1)

Notably, several features that did not reach statistical significance in the inference model (1-palmitoyl-2-dihomo-linolenoyl-GPC (16:0/20:3n3 or 6)*, p = 0.074; 1-stearoyl-2-arachidonoyl-GPC, p = 0.108; glycerate, p = 0.171) remained key contributors to the predictive performance of the ML model.

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