A berberine-loaded hydrogel for the treatment of atopic dermatitis through antibacterial activity, inhibition of inflammation and modulation of oxidative stress.

Front Immunol · 2026 · PMC12867787 · PMID 41646846

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did not reach statistical significanceno p-value reported

Compared with the control group, the levels of GSH, CAT, and the NAD + /NADH ratio were significantly reduced in the AD model group, and treatment with BHG restored these parameters toward normal levels, although the differences did not reach statistical significance ( Figures 6B–D ).

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a decreasing trendno p-value reported

No significant differences in body weight were observed among the groups; however, a decreasing trend was noted in both the model and Dex groups ( Figure 3C ).

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