Barely Significant
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Clinical characteristics associated with somatic <i>GNAS</i> mutations in acromegaly: a systematic review and institutional experience.

Front Endocrinol (Lausanne) · 2026 · PMC12867796 · PMID 41648725

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did not reach statistical significanceno p-value reported
However, while GH reduction with acute octreotide administration was greater in the patients with GNAS + tumors, this difference did not reach statistical significance.

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