Distinct clinical and inflammatory signatures in anterior vs. posterior circulation strokes.

Baseline NIHSS score emerged as a highly significant predictor of stroke location (OR = 1.20, 95% CI: 1.13–1.27, p < 0.001), with higher scores strongly associated with an increased likelihood of AC stroke.

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However, age, atrial fibrillation, and previous stroke history did not reach statistical significance as independent predictors in this model. 3.4 Differences in outcome measures between anterior and posterior stroke groups Significant differences were observed between the AC and PC stroke groups in terms of NIHSS scores at discharge, CRP levels, and WBC counts ( Table 4 ).

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