Hippocampal microstructure as a measure of cognitive resilience to tau PET burden in older adults.

J Prev Alzheimers Dis · 2026 · PMC12869048 · PMID 41494889

Europe PMC DOI

hedged sentence

0.0730

closest p · 1.5× alpha

0.0730

boldest claim

The sentences

did not reach statistical significancep = 0.073so close (0.05 < p ≤ 0.1)

Finally, the moderating effect of hippocampal MD on the relationship between average Braak I–III tau burden and odds of MCI diagnosis was attenuated, although the effect did not reach statistical significance (β = 6.33, 95 % CI [1.67, 17.27], p = 0.073).

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