Integrative single-cell analysis uncovers distinct tumour microenvironment ecotypes and immune evasion across skin cancers.

Clin Transl Med · 2026 · PMC12869349 · PMID 41636115

Europe PMC DOI

hedged sentence

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

showed a trendp = .057so close (0.05 < p ≤ 0.1)

Notably, we found that a high c1_Mel signature score was significantly associated with worse survival ( p = .00062), whereas a high c2_Mel signature score showed a trend towards improved survival outcomes ( p = .057), corresponding with its high enrichment feature in adjacent normal skin.

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