The spatial immune landscape predicts outcome and reveals the central role of tumor-associated macrophages in inflammatory breast cancer biology.

Breast Cancer Res · 2026 · PMC12870415 · PMID 41491840

Europe PMC DOI

hedged sentences

0.0250

closest p · 0.5× alpha

0.0610

boldest claim

The sentences

showed a trendP = 0.025actually significant

Although the presence of TAMs in both the TA and IM showed a trend towards shorter OS, the TA/IM ratio indicated that a greater influx of TAMs from the IM to the TA corresponded with better OS (HR: 0.56, 95% CI: 0.34–0.94, P = 0.025).

also in 22,539 other papers

borderline significanceP = 0.061so close (0.05 < p ≤ 0.1)

However, the association with lower B-cell infiltration showed only borderline significance (HR: 2.92, 95% CI: 0.9–9.45, P = 0.061).

also in 2,377 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.