Association between stress hyperglycemia ratio and mortality of traumatic brain injury patients based on MIMIC-IV and eICU databases.

Similarly, the mortality risk associated with SHR was more pronounced among patients with lower illness severity (APS III < 38) (HR 4.02, 95% CI 1.39–11.64, P = 0.01) compared with those with higher APS III scores (HR 1.04, 95% CI 0.94–1.15, P = 0.502), with a significant interaction (P for interaction = 0.012).For other subgroups—including age strata, congestive heart failure, peripheral vascular disease, hypertension, chronic pulmonary disease, renal disease, diabetes, and liver disease—the associations between SHR and mortality were directionally similar but did not reach statistical significance (all P for interaction > 0.05).

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