Sperm DNA fragmentation and assisted reproduction: an umbrella meta-analysis.

Eur J Med Res · 2026 · PMC12870536 · PMID 41501955

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did not reach statistical significanceno p-value reported

For live birth, the evidence was less consistent: Although IVF cycles showed a significant reduction in LBR with high SDF, the overall pooled estimates did not reach statistical significance, and CIs frequently crossed unity.

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