Basal metabolic rate as a protective factor against osteoporosis: a multi-cohort longitudinal study from three international aging databases.

Front Nutr · 2026 · PMC12872545 · PMID 41660419

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

a borderline significant trendp = 0.070so close (0.05 < p ≤ 0.1)

In the fully adjusted model (Model 4), which included demographics, lifestyle factors, and comorbidities, significant inverse association remained evident in the combined analysis (Q2: HR 0.841, 95% CI: 0.741–0.954, p = 0.007; Q3: HR 0.817, 95% CI: 0.686–0.972, p = 0.023), with a borderline significant trend for Q4 (HR 0.800, 95% CI: 0.629–1.018, p = 0.070).

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highly significantno p-value reported

Statistical testing confirmed highly significant differences in BMR distributions between sarcopenia groups across all analyses.

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