Personalized tumor-informed circulating tumor DNA monitoring for early detection of recurrence in postoperative pancreatic cancer.

Front Oncol · 2026 · PMC12872575 · PMID 41659718

Europe PMC DOI

hedged sentence

0.1220

closest p · 2.4× alpha

0.1220

boldest claim

The sentences

did not reach statistical significancep = 0.122not close (p > 0.1)

The difference in mDFS between recurrent patients with and without ctDNA detected at landmark time points was more than twofold but did not reach statistical significance (13.77 months vs . 5.23 months; HR: 2.224; 95% CI: 0.661 to 7.482; p = 0.122; Figure 3D ).

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