Performance of successive generative pretrained transformers (GPT) models in medical cases and board style questions.

Sci Rep · 2026 · PMC12873197 · PMID 41495183

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Taken together, the results indicate a clear trend of increasing diagnostic accuracy with successive GPT generations, with GPT-o3, GPT-4.1, and GPT-5 demonstrating significantly higher performance than their predecessors.

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