A notable trend indicated that higher levels of ALT were associated with an increasing number of G alleles in the PNPLA3 gene (Kruskal–Wallis H(2) ═ 8.10, P ═ 0.017).
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Genetic risk of alcohol-related liver cirrhosis: Associations of <i>PNPLA3</i>, <i>TM6SF2</i>, and a two-variant polygenic risk score.
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The sentences
As the number of G alleles of the PNPLA3 rs738409 increased, a significant trend toward elevated serum levels of ALT was observed.