Anti-VEGF versus laser therapy for retinopathy of prematurity: a systematic review and meta-analysis focusing on recurrence patterns and retreatment needs.

Int J Retina Vitreous · 2026 · PMC12875000 · PMID 41618478

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showed a trendno p-value reported

Zone II ROP treated with anti-VEGF agents had significantly higher recurrence rates (RR 3.42) compared to laser therapy, whereas Zone I showed a trend toward lower recurrence with anti-VEGF (RR 0.52, though not statistically significant).

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