A novel SO2 probe inhibits lysophagy induced by Senecavirus A infection by promoting LAMP1 Cys375 sulfenylation.

PLoS Pathog · 2026 · PMC12875573 · PMID 41642933

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showed a trendno p-value reported

In contrast, mutations at positions 25, 41, 80, 155, and 191, were still able to show a decrease in ubiquitination levels after DLC treatment, whereas the ubiquitination at positions 231, 269, and 338 was not significantly different from that of the wild type, and none of them showed a trend similar to that observed in C375A mutant.

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