(4) While deciding the impact of celecoxib or IL17 inhibition, looking at the cumulative readout of lung CFU, spleen CFU, Ly6G + cell recruitment, Ly6G + cell-resident Mtb pool and overall pathology, the effects are quite significant.
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Ly6G<sup>+</sup> granulocytes-derived IL-17 limits protective host responses and promotes tuberculosis pathogenesis.
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