Effect of Multidomain Intervention, Omega-3 Polyunsaturated Fatty Acids Supplementation or their Combinaison on Cognitive Function in Non-Demented Older Adults According to Frail Status: Results from the MAPT Study.

J Nutr Health Aging · 2018 · PMC12876387 · PMID 30272094

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a trend toward significanceno p-value reported

A trend toward significance difference in TMT-A were found for the effect of the MI between the two groups (pre-frail or not).

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showed a trendno p-value reported

This hypothesis is based on data from the Multidomain Alzheimer Preventive Trial (MAPT) [Therefore the results were recently published ( 6 ) and the findings for the primary outcome (the change from baseline to 36 months in a composite Z score combining four cognitive tests) were negative], in which participants on MI showed a trend towards less cognitive decline over 36 months in comparison to subjects on placebo.

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