The Molecular and Functional Landscape of Resistance to FOLFIRI Chemotherapy in Metastatic Colorectal Cancer.

Cancer Discov · 2026 · PMC12877753 · PMID 40981426

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nominally significantno p-value reported

Specifically, 11 of the 22 genes upregulated in resistant models and 23 of the 40 genes upregulated in sensitive models demonstrated nominally significant associations with the magnitude and direction of treatment response across the entire cohort (Supplementary Fig.

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