Also VLDL-TG (1.22 vs 1.01; p=0.0973) and larger VLDL (1.40 vs 1.14; p=0.0726) showed a trend to be higher in the MCI group than in the controls.
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Mild cognitive impairment associates with concurrent decreases in serum cholesterol and cholesterol-related lipoprotein subclasses.
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Conclusion These findings suggest that a decreasing trend in serum cholesterol measures in elderly individuals may suffice as an indication for more detailed inspection for potential signs of cognitive decline.
In addition, smaller VLDL subclass (-13% vs +4%; p=0.0641) and HDL-C (-3% vs + 10%, p=0.0555) had a decreasing trend in the MCI and an increasing trend in the control group.