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Benzodiazepine-related polysubstance use and hospital resource utilization in older trauma patients: a retrospective multicenter study.

Trauma Surg Acute Care Open · 2026 · PMC12878230 · PMID 41659916

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Sensitivity analyses restricted to patients aged ≥65 years showed an even stronger association between PSB+ use and ICU admission (OR 3.35, 95% CI 1.32 to 8.51, p=0.01) as well as an increased odds of mechanical ventilation (OR 8.10, 95% CI 0.99 to 65.7, p=0.05), but it did not reach statistical significance.

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