An Association Between Haemochromatosis Genotypes and Venous Leg Ulcers in Australian Individuals.

Wound Repair Regen · 2026 · PMC12878799 · PMID 41646017

Europe PMC DOI

hedged sentences

0.0811

closest p · 1.6× alpha

0.0811

boldest claim

The sentences

did not reach statistical significancep = 0.0811so close (0.05 < p ≤ 0.1)

[ 20 ] study population (14.1%); however, this difference did not reach statistical significance ( p = 0.0811) [ 20 ].

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highly significantno p-value reported

The combined frequency of the two genotypes most closely associated with haemochromatosis, p.C282Y homozygous (HH/YY) and p.H63D/p.C282Y compound heterozygous (HD/CY), was significantly higher in the VLU cohort compared with all three Australian population studies, with an OR close to four with all three studies and highly significant p ‐values (Tables 3 and 4 ). 4.

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