Barely Significant
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Blood DNA methylation-predicted plasma protein levels and colorectal cancer survival.

Clin Epigenetics · 2026 · PMC12879400 · PMID 41622289

Europe PMCDOI
1
hedged sentence
0.0014
closest p · 0.0× alpha
0.0014
boldest claim

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did not reach statistical significanceP = 0.0014actually significant
Protein episcores and CRC overall survival In Cox regression models adjusted for age at diagnosis, the Protein EpiScores for LGALS3BP and VEGFA appeared associated with higher mortality risk, but these associations did not reach statistical significance after adjustment for multiple comparisons (LGALS3BP, HR: 1.61, 95% CI 1.20, 2.15, P = 0.0014, FDR = 0.15; VEGFA, HR: 1.62, 95% CI 1.20, 2.19, P = 0.0016, FDR = 0.17) (Fig. 3 ).

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