Mutational landscape and risk estimates of DDR genes in Chinese ovarian cancer patients.

For other DDR genes—including BRIP1 , ERCC3 , RAD54L , FANCL , TP53 , MRE11A , FANCM , MSH6 , RAD50 , ATM , and FANCA —the ORs exceeded 2, but their associations with OC risk did not reach statistical significance (Table 2 and Table S4).

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Similarly, although BRIP1 showed borderline significance when compared with the gnomAD database, the association was no longer statistically significant after Benjamini–Hochberg correction for multiple testing.

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