Our hypothesis is based on data from the Multidomain Alzheimer Preventive Trial (MAPT), in which participants on n-3 PUFA supplementation with a low omega-3 index (≤ 4.83 %: lowest quartile of omega 3 index distribution) at baseline, showed a trend towards less cognitive decline over 36 months in comparison to subjects on placebo with low baseline omega-3 index (p for interaction = 0.065) ( 9 ).
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Cognitive Changes with Omega-3 Polyunsaturated Fatty Acids in Non-Demented Older Adults with Low Omega-3 Index.
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