Barely Significant
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The effects of GLP-1 receptor agonists on metabolic inflammatory markers in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.

PeerJ · 2026 · PMC12880101 · PMID 41660088

2
hedged sentences
0.2100
closest p · 4.2× alpha
0.2100
boldest claim

The sentences

a decreasing trendP = 0.21not close (p > 0.1)
Although the results from 13 studies indicated a decreasing trend in IL-6 levels (SMD = −0.52), this change was not statistically significant (95% CI [−1.34 to 0.29], P = 0.21, I 2 = 96%).

also in 47,180 other papers

did not reach statistical significancep = 0.21not close (p > 0.1)
By contrast, changes in interleukin-6 (IL-6) were inconsistent across trials and did not reach statistical significance ( p = 0.21).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.