Relationship between low relative muscle mass and aortic regional morphological changes in adults underwent contrast CT scans for cancer diagnostics.

We also observed linear and negative associations of the standardized muscle volume with the diameter in L1, L3 (r = −0.22, p = 0.001; r = −0.18, p = −0.011) and tortuosity of the total aorta (r = −0.30, p < 0.001), DTA (r = −0.34, p < 0.001) and AA (r = −0.28, p < 0.001); there was a negative association between standardized muscle volume with the diameter in L2 (r = −0.13, p = 0.061), but did not reach statistical significance; as shown in Supplementary Figure S4. 3.5 Intra- and interobserver variability The intraobserver reliability for measuring L1-5 and aortic tortuosity was excellent, with values ranging from 0.963 to 0.998.

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