Barely Significant
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Altered serum short-chain fatty acid profiles in episodic and chronic migraine and their modulation by preventive treatment.

J Headache Pain · 2026 · PMC12882297 · PMID 41514240

Europe PMCDOI
1
hedged sentence
0.0540
closest p · 1.1× alpha
0.0540
boldest claim

The sentences

did not reach statistical significancep = 0.054so close (0.05 < p ≤ 0.1)
Although the interaction term did not reach statistical significance (B = 0.596, 95% CI: − 0.011 to 1.203, p = 0.054), subgroup analyses showed that preventive treatment was significantly associated with higher propionate levels in the CM group (B = 0.805, 95% CI: 0.395 to 1.215, p < 0.001), but not in the EM group (B = 0.217, 95% CI: − 0.236 to 0.669, p = 0.346) (Supplementary Table 11 ).

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