In contrast, among patients aged ≥ 1 year, the distribution of total biopterin levels showed a trend similar to that of baseline Phe concentrations (1–5 years: median 22.66 nM [IQR: 14.18–50.46]; 6–11 years: 40.50 nM [29.43–57.25]; 12–19 years: 45.76 nM [26.58–60.06]; ≥ 20 years: 36.46 nM [27.81–52.83]).
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Age-Dependent Variation in Blood Biopterin Peaks Following Oral Tetrahydrobiopterin Administration in Phenylketonuria.
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