Clinical features and comorbidities of Epstein-Barr virus infection in childhood-onset systemic lupus erythematosus with a focus on macrophage activation syndrome: a cross-sectional study of 200 patients.

Front Immunol · 2026 · PMC12883786 · PMID 41668759

Europe PMC DOI

hedged sentence

0.0703

closest p · 1.4× alpha

0.0703

boldest claim

The sentences

a strong trendP = 0.0703so close (0.05 < p ≤ 0.1)

Our data support this mechanism, as patients in the MAS group had a significantly higher percentage of CD8 + T cells ( P = 0.004), and an elevated CD8 + T-cell percentage showed a strong trend toward being a risk factor for MAS in the multivariate analysis ( P = 0.0703).

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