Although no statistically significant difference was observed when comparing post-switch assessments to the time of switch, an increasing trend in both HFMSE and RULM scores was evident.
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Treatment of risdiplam after nusinersen continuously improves upper limb motor function in spinal muscular atrophy patients: a multicenter experience.
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The sentences
Although these changes did not reach statistical significance, a consistent upward trend in HFMSE scores was observed following the switch and throughout the observation period ( Figures 2A,B and Supplementary Table S2 ).
In the only patient who completed the 6MWT assessment, we observed a positive trend.