A favorable trend toward improved PFS with D-VRd compared with VRd was also observed in CTC-high patients.
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Circulating tumor cells predict myeloma outcomes in patients treated with daratumumab, bortezomib, lenalidomide, and dexamethasone.
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D-VRd improved and sustained MRD-negativity rates in CTC-high and CTC-low, and improved PFS for CTC-low with a positive trend in CTC-high patients.
However, this did not reach statistical significance and would require longer follow-up for confirmation.