Characteristics and long-term outcomes of children with perianal Crohn's disease.

Intest Res · 2026 · PMC12884105 · PMID 40038553

Europe PMC DOI

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a clear trendno p-value reported

In the management of pediatric CD patients with PL, recent studies have suggested a clear trend towards the early introduction and increased utilization of biologic therapies, which has shown promising results [ 6 , 15 ].

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a notable trendno p-value reported

The evolving landscape of CD management in patients with PL is characterized by a notable trend towards early introduction and increased utilization of biologic therapies [ 13 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.