Barely Significant
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MiR-424-5p acts as an oncogene in Hep3B cells by activating the PI3K/AKT signaling pathway.

Front Oncol · 2025 · PMC12884537 · PMID 41669257

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hedged sentence
0.0680
closest p · 1.4× alpha
0.0680
boldest claim

The sentences

did not reach statistical significanceP = 0.068so close (0.05 < p ≤ 0.1)
Although a similar trend was observed in an independent validation cohort (HR = 1.44, 95% CI: 0.97–2.15), the difference did not reach statistical significance (P = 0.068) ( Figure 1D ), which may be attributable to limited sample size or inherent cohort heterogeneity.

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