Opicapone for the Treatment of Nocturnal Hypokinesia in Patients With Parkinson's Disease: An Open-Label Pilot Clinical Trial.

J Mov Disord · 2026 · PMC12885641 · PMID 41261362

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did not reach statistical significanceno p-value reported

These general sleep questionnaires do not include NH-specific questions except Item 9 of the PDSS-2—“Did you feel uncomfortable at night because you were unable to turn around in bed or move due to immobility?” [ 8 ] This may partially explain why changes in these secondary outcomes did not reach statistical significance in the present study.

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