Long-term outcomes and patient profiles following intensity-modulated radio-chemotherapy for nasopharyngeal cancer in a nonendemic region.

Front Oncol · 2026 · PMC12885988 · PMID 41675289

Europe PMC DOI

hedged sentences

0.0550

closest p · 1.1× alpha

0.0580

boldest claim

The sentences

a trend toward significancep = 0.055so close (0.05 < p ≤ 0.1)

In multivariable analysis, metastatic recurrence was the strongest independent predictor of death (HR 37.1; 95% CI 7.29–189; p < 0.001), local recurrence showed a trend toward significance (HR 0.26; 95% CI 0.07–1.03; p = 0.055), and status at last follow-up remained highly predictive of survival (HR 0.01; 95% CI 0.00–0.04; p < 0.001).

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showed a trendp = 0.058so close (0.05 < p ≤ 0.1)

Tobacco use showed a trend toward poorer OS for current smokers (HR 2.91; 95% CI 0.97–8.80; p = 0.058).

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