Nociplastic pain: the prominent role of non-neuronal cells in central and peripheral sensitization.

Front Immunol · 2026 · PMC12886048 · PMID 41676154

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failed to reach statistical significanceno p-value reported

While microglial proliferation has been observed in M1-mediated CRPS models, increases in phosphorylated ERK1/2 (Tyr204)/ERK1/2 failed to reach statistical significance in some studies ( 122 ).

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