Sex and menopause-based differences in presentation of early Lyme disease: A prospective cohort study.

Clin Exp Med · 2026 · PMC12886233 · PMID 41653328

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.1000

boldest claim

The sentences

a statistical trendp = 0.060so close (0.05 < p ≤ 0.1)

Among females, no acute disease symptoms were statistically significantly different by menopausal status, and only sore throat showed a statistical trend (18.0% pre- vs. 6.3% post-menopausal, p = 0.060).

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did not reach statistical significancep < 0.10so close (0.05 < p ≤ 0.1)

Photophobia, neck pain, and nausea were also reported more frequently among females, while irritability was reported more frequently among males, although these did not reach statistical significance (0.05 < p < 0.10).

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