Safety and efficacy of Cangrelor versus GPIIb/IIIa inhibitors as adjunctive therapy in endovascular treatment of acute ischemic stroke: a systematic review and meta-analysis.

Parenchymal hematoma (PH) For PH, the RR did not reach statistical significance different between the cangrelor and GPIs (RR 0.95, 95% CI [0.53,-1.72]; p = 0.87; I2=21%, Fig. 5 d) Discussion EVT is a cornerstone in the management of complex vascular cases, including acute stroke, intracranial aneurysms, and advanced peripheral arterial disease [ 22 ], and the choice of antiplatelet therapy in this context is critical, as it directly influences the balance between preventing vessel re-occlusion (thrombosis) and minimizing bleeding complications [ 23 ].

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